Cervsure Human Papillomavirus (HPV)
Screening Real-Time PCR Kit (18 Genotypes)
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SKU
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100 Rxns : CVHPS24007
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Cervsure Human Papillomavirus (HPV) Screening Real-Time PCR Kit is a multiplex TaqMan Probe-based Real-Time PCR kit for detecting and differentiating HPV 16 and 18 and screening 16 High-risk genotypes along with Human internal control.
Features
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Multiplex TaqMan RT-PCR Assay for detecting target sequences in HPV 16 and 18 & screening 16 High-risk genotypes
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Internal control: Beta Actin
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PCR Run Time: 60 Minutes
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Sample Type: DNA Extracted from human cervical swabs and oral swabs
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System Compatibility: Real-time PCR instruments with FAM, HEX, CY5 & Texas Red/ROX channels.
Storage & Precautions
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Recommended Storage: -20°C
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For Professional Use only.
Clinical Relevance
Human Papillomavirus (HPV) is the leading cause of Cervical Cancer, and the most common sexually transmitted infection (STI). Over 50% of sexually active women are infected at some point in their lives, with 10-20% developing persistent infection.
HPV types 16 and 18 have been regarded as high-risk cancer-associated types and HPV types 31, 33, and 35 have been demonstrated to have an intermediate association with cancer. Persistent infection with a group of “high-risk” HPVs may lead to Cervical Cancer.
HPV genotype screening and detection is crucial in patient management, enabling gynecologists to determine treatment regimes before lesions undergo invasive changes. Latest reports suggest HPV-16 is the most prevalent (>85%) genotype detected in India among other genotypes.